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When the pH of the ECF decreases, K+ starts to move from the


A) ECF to the ICF.
B) ICF to the ECF.

C) A) and B)
D) undefined

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Hyperventilation leads to respiratory alkalosis.

A) True
B) False

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An accumulation of fluid in one area of the body, such that the fluid is not available for use elsewhere, is known as fluid ________.

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Facultative water loss is loss that


A) occurs regardless of the state of hydration of the body.
B) is controlled by hormone effects on the kidney.
C) occurs through sweating and breathing.

D) A) and B)
E) None of the above

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Which ion is the principal solute of the ECF and is crucial for neuromuscular and renal function?


A) Magnesium
B) Phosphate
C) Calcium
D) Sodium
E) Potassium

F) B) and D)
G) A) and E)

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If a physiologic condition resulted in blood pH reaching 7.2, but then physiological buffering systems brought the pH to 7.4, that increase in pH would be called


A) acidosis.
B) alkalosis.
C) compensation.
D) imbalance.
E) partial noncompensation.

F) D) and E)
G) None of the above

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Angiotensin II triggers


A) vasoconstriction and increased urine output from the kidneys.
B) vasoconstriction and decreased urine output from the kidneys.
C) vasodilation and increased urine output from the kidneys.
D) vasodilation and decreased urine output from the kidneys.

E) A) and B)
F) A) and C)

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An individual who consumes many antacids for stomach upset and many diuretics for high blood pressure will be at risk for metabolic


A) acidosis.
B) alkalosis.

C) A) and B)
D) undefined

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If a strong acid were to add H+ to the intracellular fluid, the effect would most likely be buffered, because


A) HPO42- would act as a weak acid and donate an H+ to become PO4-.
B) HPO42- would act as a weak base and accept an H+ to become H2PO4-.
C) H2PO4- would act as a weak acid and accept an H+ to become H3PO4-.
D) PO4 would act as a strong base and accept an H+ to become HPO4.

E) A) and C)
F) A) and B)

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If someone runs a marathon through a desert while eating pretzels and not drinking water, their plasma osmolarity


A) rises and becomes hypertonic to the interstitial and intracellular fluid compartments.
B) rises and becomes hypotonic to the interstitial and intracellular fluid compartments.
C) decreases and becomes hypertonic to the interstitial and intracellular fluid compartments.
D) decreases and becomes hypotonic to the interstitial and intracellular fluid compartments.

E) A) and C)
F) C) and D)

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A comparison of the two major body fluid compartments reveals that


A) two-thirds of the total fluid is outside our cells and one-third is within our cells.
B) two-thirds of the total fluid is within our cells and one-third is outside our cells.
C) half of the total fluid is within our cells and half is outside our cells.
D) six-sevenths of the total fluid is within our cells and one-seventh is outside our cells.
E) six-sevenths of the total fluid is outside our cells and one-seventh is within our cells.

F) None of the above
G) B) and E)

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To account for their effects on osmotic pressure, the concentration of electrolytes is often expressed in


A) moles.
B) moieties.
C) milliequivalents per liter.
D) moles per liter.
E) milliliters.

F) B) and E)
G) A) and E)

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Most potassium loss from the body occurs through


A) sweat.
B) urine.
C) feces.
D) respiration.

E) A) and D)
F) A) and C)

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The amine groups contained within amino acids of proteins can act as weak


A) acids.
B) bases.

C) A) and B)
D) undefined

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A diet rich in animal protein contributes to increased levels of


A) volatile acid.
B) bicarbonate ions.
C) fixed acid.

D) All of the above
E) B) and C)

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When blood starts to become too acidic, the kidneys respond by


A) synthesizing and secreting bicarbonate ions while reabsorbing H+.
B) synthesizing and reabsorbing H+ while filtering bicarbonate ions.
C) synthesizing and reabsorbing bicarbonate ions while secreting H+.
D) decreasing filtration rate and increasing reabsorption of both bicarbonate ions and H+.
E) increasing filtration rate and increasing reabsorption of H+.

F) A) and D)
G) None of the above

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The most abundant anion in the extracellular fluid is


A) negatively charged proteins.
B) phosphate.
C) chloride.
D) hydrogen.
E) acetic acid.

F) A) and C)
G) A) and B)

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When physiological systems cannot compensate for an acid-base disturbance, and the deviation from normal pH becomes more persistent, it is referred to as an acid-base ________.

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The stimuli that trigger the release of ADH are


A) high blood pressure, high blood volume, and high blood osmolarity.
B) high blood pressure, low blood volume, and low blood osmolarity.
C) low blood pressure, low blood volume, and high blood osmolarity.
D) low blood pressure, high blood volume, and high blood osmolarity.
E) low blood pressure, low blood volume, and low blood osmolarity.

F) A) and E)
G) A) and D)

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Water lost through feces is considered ________ water loss.


A) sensible, obligatory
B) sensible, facultative
C) insensible, obligatory
D) insensible, facultative

E) B) and D)
F) All of the above

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