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Which of the following structures would be expected to develop normally in individuals with the DiGeorge's syndrome?


A) Aortic arches
B) Parathyroid glands
C) Thymus
D) Truncus arteriosus
E) Parotid gland

F) A) and B)
G) B) and C)

Correct Answer

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In bilateral cleft lip,the clefts are typically found between the _______________.


A) Central incisor teeth
B) Central and lateral incisor teeth
C) Lateral incisor and canine teeth
D) Canine and first molar teeth
E) First and second molar teeth

F) A) and B)
G) A) and C)

Correct Answer

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C

Which of the following associations is correct?


A) Enamel - Oral ectoderm; Dentine - Oral ectoderm
B) Enamel - Oral ectoderm; Dentine - Cranial mesoderm
C) Enamel - Neural crest ectoderm; Dentine - Neural crest ectoderm
D) Enamel - Oral ectoderm; Dentine - Neural crest ectoderm
E) Enamel - Neural crest ectoderm; Dentine - Cranial mesoderm

F) A) and B)
G) A) and C)

Correct Answer

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An oblique facial cleft is due to incomplete fusion of the ____________.


A) Nasolateral process with maxillary process
B) Nasomedial process with mandibular process
C) Nasomedial process with nasolateral process
D) Nasomedial process with maxillary process
E) Nasolateral process with mandibular process

F) B) and D)
G) A) and E)

Correct Answer

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The greater horn (cornu) of the hyoid bone is a derivative of the ____________ pharyngeal arch.


A) First
B) Second
C) Third
D) Fourth
E) Sixth

F) B) and E)
G) A) and C)

Correct Answer

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Defective formation of the forebrain is the underlying cause of _____________.


A) Oblique facial cleft
B) Cleft palate
C) Holoprosencephaly
D) Treacher Collins syndrome
E) Agnathia

F) A) and B)
G) A) and C)

Correct Answer

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The earliest induction in tooth development consists of the ectoderm of the dental epithelium acting on the underlying neural crest mesenchyme.Which of the following molecules is an important mediator of the inductive stimulus?


A) Bone morphogenetic protein-4
B) Sonic hedgehog
C) Hoxb
D) Hoax
E) Pax-6

F) A) and B)
G) A) and C)

Correct Answer

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In cases of holoprosencephaly,defects of facial structures are typically secondary to defects of the ________________.


A) Pharynx
B) Oral cavity
C) Forebrain
D) Eyes
E) Hindbrain

F) C) and E)
G) B) and C)

Correct Answer

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The facial (VII) nerve supplies muscles derived from the ______________ pharyngeal arch.


A) First
B) Second
C) Third
D) Fourth
E) Sixth

F) C) and E)
G) All of the above

Correct Answer

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The foramen cecum represents the original location of the primordium of the ____________.


A) Thymus
B) Parathyroid glands
C) Thyroid gland
D) Anterior lobe of pituitary gland
E) Posterior lobe of pituitary gland

F) B) and C)
G) A) and C)

Correct Answer

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In keeping with its embryological origin,the sensory innervation of the body of the tongue is from cranial nerve __________.


A) V
B) VII
C) IX
D) X
E) XII

F) B) and C)
G) D) and E)

Correct Answer

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Most of the facial muscles arise from the ______________.


A) Neural crest
B) Somites
C) Somitomeres
D) Splanchnic mesoderm

E) B) and D)
F) All of the above

Correct Answer

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Meckel's cartilage is a prominent component during the early formation of the ____________.


A) Upper jaw
B) Lower jaw
C) Nasal septum
D) Hard palate
E) Soft palate

F) A) and B)
G) B) and C)

Correct Answer

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B

Dentin is secreted by cells derived from the ________________.


A) Ectoderm
B) Mesoderm
C) Endoderm
D) Neural crest
E) None of the above

F) C) and D)
G) A) and B)

Correct Answer

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A patient reports a painful swelling located between the angle of the jaw and the sternocleidomastoid muscle.Her physician determines that the pathology is congenital in origin.What is the most likely problem?


A) Persistence of the thyroglossal duct
B) Persistence of the third pharyngeal pouch
C) DiGeorge's syndrome
D) Hypertelorism
E) None of the above

F) A) and B)
G) A) and E)

Correct Answer

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Cyclopia,an extreme form of holoprosencephaly,results from a lack of ____________.


A) Pax-2
B) Wnt-2
C) Msx-1
D) Sonic hedgehog
E) Fibroblast growth factor-4

F) C) and D)
G) B) and E)

Correct Answer

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Activity of which molecule steers the differentiation of pancreatic progenitor cells toward the exocrine pathway?


A) Neurogenin-3
B) Pax-6
C) Pax-4
D) Notch
E) None of the above

F) A) and D)
G) All of the above

Correct Answer

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The philtrum of the lip is formed by the _______________.


A) Frontonasal prominence
B) Nasomedial processes
C) Nasolateral processes
D) Primary palate
E) Nasolacrimal groove

F) C) and E)
G) A) and E)

Correct Answer

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B

The nasolacrimal duct arises as a furrow located between the ________________.


A) Maxillary process and mandibular arch
B) Nasomedial and nasolateral processes
C) Forebrain prominence (frontonasal process) and maxillary process
D) Nasolateral and maxillary processes
E) Forebrain prominence (frontonasal process) and nasomedial process

F) A) and E)
G) C) and D)

Correct Answer

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Which family of molecules is heavily involved in patterning along the (proximodistal) length of the embryonic mandible?


A) Dlx
B) Otx
C) Hedgehog
D) Msx
E) None of the above

F) A) and E)
G) D) and E)

Correct Answer

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