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The classical pathway for complement activation is initiated by


A) lipid-carbohydrate complexes and C3.
B) C5-C9.
C) antigen-antibody reactions.
D) factors released from phagocytes.
E) factors released from damaged tissues.

F) C) and D)
G) A) and B)

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Activation of C3a results in


A) acute inflammation.
B) increased blood vessel permeability.
C) opsonization.
D) attraction of phagocytes.
E) cell lysis.

F) A) and C)
G) None of the above

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All of the following are components of the inflammatory process EXCEPT


A) dilation of blood vessels.
B) release of histamines and prostaglandins.
C) chemotaxis.
D) diapedesis.
E) antibody synthesis.

F) A) and B)
G) B) and E)

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Which non-specific defense mechanism is mismatched with its associated body structure or body fluid?


A) lysozyme - tears and saliva
B) mucociliary escalator - intestines
C) very acidic pH - stomach
D) keratin and tightly packed cells - skin
E) cerumen and sebum - ear

F) B) and C)
G) A) and E)

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Which of the following exhibits the highest phagocytic activity?


A) eosinophils
B) erythrocytes
C) macrophages
D) basophils
E) neutrophils

F) A) and B)
G) None of the above

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Which of the following is mismatched?


A) diapedesis - movement of leukocytes between capillary walls cells out of blood and into tissue
B) chemotaxis - chemical degradation inside a phagolysosome
C) abscess - a cavity created by tissue damage and filled with pus
D) pus - tissue debris and dead phagocytes in a white or yellow fluid
E) scab - dried blood clot over injured tissue

F) A) and B)
G) B) and E)

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The alternative pathway for complement activation is initiated by


A) lipid-carbohydrate complexes and C3.
B) C5-C9.
C) antigen-antibody reactions.
D) factors released from phagocytes.
E) factors released from damaged tissues.

F) A) and E)
G) C) and D)

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Normal microbiota provide protection from infection in each of the following ways EXCEPT


A) they produce antibacterial chemicals.
B) they compete with pathogens for nutrients.
C) they make the chemical environment unsuitable for nonresident bacteria.
D) they produce lysozyme.
E) they change the pH of the environment.

F) A) and C)
G) A) and B)

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TLRs attach to all of the following EXCEPT


A) AMPs.
B) flagellin.
C) LPS.
D) PAMPs.
E) peptidoglycan.

F) D) and E)
G) C) and E)

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The swelling associated with inflammation decreases when the fluid


A) returns to the blood.
B) goes into lymph capillaries.
C) is excreted in urine.
D) is lost as perspiration.
E) is transported into macrophages.

F) B) and C)
G) C) and E)

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Innate immunity includes all of the following EXCEPT


A) phagocytosis.
B) inflammation.
C) production of antibody.
D) production of interferon.
E) activation of complement.

F) A) and D)
G) B) and D)

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The complement system is extremely important in the innate defense response.It can be said that this system is a cascade system.Explain this statement.

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The complement system is a crucial compo...

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A chill is a sign that


A) body temperature is falling.
B) body temperature is rising.
C) body temperature is not changing.
D) the metabolic rate is decreasing.
E) blood vessels are dilating.

F) None of the above
G) All of the above

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A differential cell count is used to determine each of the following EXCEPT


A) the total number of white blood cells.
B) the numbers of each type of white blood cell.
C) the number of red blood cells.
D) leukocytosis.
E) leukopenia.

F) B) and D)
G) B) and E)

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If you were interested in seeking new sources of antimicrobial drugs from natural sources,you might look to antimicrobial peptides.Identify possible sources for these drugs,and then describe how you might go about testing for their desired effects.

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Possible sources for antimicrobial pepti...

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All of the following increase blood vessel permeability EXCEPT


A) kinins.
B) prostaglandins.
C) lysozymes.
D) histamine.
E) leukotrienes.

F) B) and E)
G) C) and D)

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Lysozyme and the antibiotic penicillin have similar mechanisms of action in that they both cause damage to the bacterial


A) cell membrane.
B) capsule.
C) cell wall.
D) DNA.
E) ribosomes.

F) A) and E)
G) A) and B)

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The function of the "ciliary escalator" is to


A) propel inhaled dust and microorganisms away from the mouth,toward the lower respiratory tract.
B) remove microorganisms from the gastrointestinal tract.
C) remove microorganisms from the lower respiratory tract.
D) trap microorganisms in mucus in the upper respiratory tract.
E) trap inhaled dust and microorganisms in mucus and propel it away from the lower respiratory tract.

F) B) and D)
G) A) and B)

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Microorganisms that are members of the normal microbiota are also known to cause disease.

A) True
B) False

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Neutrophils with defective lysosomes are unable to


A) undergo chemotaxis.
B) migrate.
C) produce toxic oxygen products.
D) attach to microorganisms and other foreign material.
E) engulf microorganisms and other foreign material.

F) All of the above
G) A) and D)

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