Question 1

Class I viruses,double-stranded DNA viruses,usually utilize the following polymerases for mRNA synthesis and DNA replication

Accepted Answer

A)   host cell DNA-dependent RNA polymerase and host cell DNA-dependent DNA polymerase.
B)   viral DNA-dependent RNA polymerase and viral DNA-dependent DNA polymerase.
C)   viral RNA-dependent RNA polymerase and host cell DNA-dependent DNA polymerase.
D)   host cell RNA-dependent RNA polymerase and host cell DNA-dependent DNA polymerase.
E)   viral RNA-dependent RNA polymerase and viral DNA-dependent DNA polymerase.F) A) and B)
G) B) and E)

Question 2

Host __________ is determined through the specific binding of the viral attachment protein to the host cell receptor.

Accepted Answer

range or s...

Question 3

Most enveloped viruses exit the host cell through cell lysis.

Accepted Answer

A) True 
 B)False

Question 4

Most likely,"host specificity" of a virus is determined by

Accepted Answer

A)   the type of nucleic acid it contains.
B)   the presence or absence of an envelope.
C)   viral enzymes.
D)   interactions between viral attachment proteins and host cell receptors.
E)   viral nucleic acid replication strategies.F) A) and B)
G) D) and E)

Question 5

Antibodies produced in response to a viral infection may specifically bind to the virus particle to effectively block _______________ to the host cell.

Accepted Answer

The answer of Antibodies produced in response to a viral...

Question 6

The influenza virus gains entry into a host cell by an endocytotic process.The viral nucleocapsid leaves the endosome and enters the cytoplasm through a membrane fusion mechanism.Fusion of the viral envelope with the endosomal membrane is facilitated by

Accepted Answer

A)   a conformation change in the hemagglutinin to expose a fusion protein.
B)   the production of a lipase by the influenza virus.
C)   sialic acid residues of the receptor proteins.
D)   specific viral protein recognition of pores in the endosome vesicle.
E)   the production of proteases by the influenza virus.F) None of the above
G) All of the above

Question 7

Phage lambda (λ) is referred to as a temperate phage.What is a temperate phage?

Accepted Answer

A)   A phage that always causes a lytic infection.
B)   The same thing as a lysogen.
C)   A phage that only lyses a cell at a specific temperature.
D)   A phage that can undergo either a lytic or lysogenic phase of replication.
E)   A bacteriophage that contains single-stranded RNA for its genome.F) A) and B)
G) A) and C)

Question 8

Describe the series of events that usually occur for an enveloped virus to exit the cell with an intact envelope containing the outer envelope viral proteins.

Accepted Answer

The series of events that usually occur ...

Question 9

Which of the following viral replication processes would not be a good target for an antiviral drug?

Accepted Answer

A)   Attachment
B)   Viral entry
C)   Translation of viral proteins
D)   Uncoating of viral capsid
E)   Assembly of virus capsidF) A) and C)
G) A) and B)

Question 10

Most non-enveloped animal viruses enter the host cell by

Accepted Answer

A)   membrane fusion.
B)   pinocytosis.
C)   injection of nucleic acid into host cell.
D)   lysis of host cell membrane.
E)   receptor mediated endocytosis.F) None of the above
G) B) and E)

Question 11

A viral fusion peptide contains a short hydrophobic amino acid sequence that helps facilitate membrane fusion of the viral envelope to the cell membrane for entry into the host cell.The protein _____________ functions as a fusion peptide for HIV entry into the host cell.

Accepted Answer

The answer of A viral fusion peptide contains a short...

Question 12

HIV enters the cell through a/an _________ mechanism.

Accepted Answer

A)   phagocytic
B)   receptor-mediated endocytotic
C)   membrane fusion
D)   acid-dependent endosomal
E)   receptor-independent endocytoticF) A) and B)
G) B) and E)

Question 13

Reverse transcriptase is an RNA-dependent DNA polymerase.

Accepted Answer

A) True 
 B)False

Question 14

A bacteriophage genome that is integrated into the bacterial chromosome is called

Accepted Answer

A)   a prophage.
B)   a virulent phage.
C)   a transforming phage.
D)   a genome phage.E) C) and D)
F) None of the above

Question 15

Plant viruses often gain entry into host cells by

Accepted Answer

A)   receptor mediated endocytosis.
B)   injury caused by insects to host cell.
C)   membrane fusion mechanism.
D)   pinocytosis.
E)   direct injection of nucleic acid into the host cell.F) A) and B)
G) A) and C)

Question 16

The capsid for many mammalian viruses must be removed after it enters the cytoplasm.Why is this important? Give an example of a virus where capsid removal occurs in the cell membrane.

Accepted Answer

The removal of the capsid for many mamma...

Question 17

The Baltimore classification scheme for viruses divides all viruses into seven groups based on

Accepted Answer

A)   their shape and host.
B)   host and presence or absence of an envelope.
C)   how they produce mRNA and replicate their genome.
D)   their shape and presence or absence of an envelope.
E)   their shape, host, and presence or absence of an envelope.F) A) and E)
G) D) and E)

Question 18

What are the functions of the retrovirus enzymes reverse transcriptase and integrase for the replication of the virus?

Accepted Answer

Retroviruses, such as HIV, have a unique...

Question 19

Most RNA viruses utilize

Accepted Answer

A)   an RNA-dependent RNA polymerase.
B)   a DNA-dependent RNA polymerase.
C)   an RNA-dependent DNA polymerase.
D)   a DNA-dependent DNA polymerase.
E)   reverse transcriptase.F) A) and C)
G) B) and D)

Question 20

Many antiviral drugs are nucleoside analogs.The nucleoside analogs primarily target these enzymes

Accepted Answer

A)   host cell DNA polymerases.
B)   host cell RNA polymerases.
C)   host cell nucleases.
D)   viral nucleic acid polymerases.
E)   viral nucleases.F) A) and B)
G) C) and E)

Exam 8: Viral Replication Strategies

Host __________ is determined through the specific binding of the viral attachment protein to the host cell receptor.

Correct Answerverifiedrange or s...View AnswerShow Answer

Most enveloped viruses exit the host cell through cell lysis.

Correct AnswerverifiedShow Answer

A viral fusion peptide contains a short hydrophobic amino acid sequence that helps facilitate membrane fusion of the viral envelope to the cell membrane for entry into the host cell.The protein _____________ functions as a fusion peptide for HIV entry into the host cell.

Correct AnswerverifiedShow Answer

The influenza virus gains entry into a host cell by an endocytotic process.The viral nucleocapsid leaves the endosome and enters the cytoplasm through a membrane fusion mechanism.Fusion of the viral envelope with the endosomal membrane is facilitated by

Correct AnswerverifiedShow Answer

Many antiviral drugs are nucleoside analogs.The nucleoside analogs primarily target these enzymes

Correct AnswerverifiedShow Answer

Most likely,"host specificity" of a virus is determined by

Correct AnswerverifiedShow Answer

The Baltimore classification scheme for viruses divides all viruses into seven groups based on

Correct AnswerverifiedShow Answer

Most RNA viruses utilize

Correct AnswerverifiedShow Answer

Antibodies produced in response to a viral infection may specifically bind to the virus particle to effectively block _______________ to the host cell.

Correct AnswerverifiedShow Answer

Phage lambda (λ) is referred to as a temperate phage.What is a temperate phage?

Correct AnswerverifiedShow Answer

Which of the following viral replication processes would not be a good target for an antiviral drug?

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The capsid for many mammalian viruses must be removed after it enters the cytoplasm.Why is this important? Give an example of a virus where capsid removal occurs in the cell membrane.

Correct AnswerAnswered by ExamLex AIThe removal of the capsid for many mamma...View AnswerShow Answer

Describe the series of events that usually occur for an enveloped virus to exit the cell with an intact envelope containing the outer envelope viral proteins.

Correct AnswerAnswered by ExamLex AIThe series of events that usually occur ...View AnswerShow Answer

Plant viruses often gain entry into host cells by

Correct AnswerverifiedShow Answer

What are the functions of the retrovirus enzymes reverse transcriptase and integrase for the replication of the virus?

Correct AnswerAnswered by ExamLex AIRetroviruses, such as HIV, have a unique...View AnswerShow Answer

Most non-enveloped animal viruses enter the host cell by

Correct AnswerverifiedShow Answer

Reverse transcriptase is an RNA-dependent DNA polymerase.

Correct AnswerverifiedShow Answer

Class I viruses,double-stranded DNA viruses,usually utilize the following polymerases for mRNA synthesis and DNA replication

Correct AnswerverifiedShow Answer

A bacteriophage genome that is integrated into the bacterial chromosome is called

Correct AnswerverifiedShow Answer

HIV enters the cell through a/an _________ mechanism.

Correct AnswerverifiedShow Answer

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range or s...
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The removal of the capsid for many mamma...
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The series of events that usually occur ...
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Retroviruses, such as HIV, have a unique...
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