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The leading reason for liver transplantation in the United States is _________.


A) hepatitis C
B) hepatitis B
C) hepatitis A
D) hepatitis D

E) B) and C)
F) B) and D)

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Women of childbearing age should be vaccinated against _________.


A) chickenpox
B) German measles
C) shingles
D) influenza A

E) B) and C)
F) A) and B)

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The rash associated with German measles is most likely caused by


A) the virus infecting the cells of the skin.
B) the virus infecting the cells of the dermal layer beneath the skin.
C) an immunological reaction to the virus.
D) All of the choices are correct.

E) B) and C)
F) A) and D)

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In those cases of pneumonia for which no cause is determined by laboratory findings,__________ pneumonia can be assumed if __________ pneumonia has been ruled out.


A) viral; mycoplasmal
B) bacterial; viral
C) mycoplasmal; viral
D) mycoplasmal; bacterial

E) C) and D)
F) B) and C)

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Acute viral gastroenteritis can be caused by the


A) norovirus and the rotavirus group.
B) cytomegalovirus and hepatitis
C) the Delta agent.
D) varicella zoster virus and rubeola virus.

E) C) and D)
F) A) and C)

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Antiviral drugs are frequently used for the treatment of infectious mononucleosis.

A) True
B) False

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Chickenpox is caused by the __________ virus.


A) rubella
B) rubeola
C) coxsackievirus B
D) varicella

E) B) and C)
F) A) and D)

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Antigenic variation is common in influenza B and C but is rare in influenza A.

A) True
B) False

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Warts or verrucae are caused by the papillomaviruses.

A) True
B) False

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The reactivated form of chickenpox is called _________.


A) rubella
B) adenovirus
C) herpes zoster
D) rubeola

E) None of the above
F) A) and B)

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A traveler returning to the United.States from India reported having a fever and severe joint pain.She mentioned that the mosquitoes had been particularly troublesome during her trip,and that she had taken the appropriate prophylactic anti-malarial medications.What is a likely cause of her illness?


A) Malaria
B) Yellow fever
C) Lyme disease
D) West Nile virus
E) Chickungunya fever

F) None of the above
G) A) and B)

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The rabies virus is transmitted to humans by


A) the bite of an infected animal.
B) aerosols of the virus that can be present in caves where bats roost.
C) contamination of scratches with saliva from an infected animal.
D) All of the choices are correct.

E) B) and D)
F) A) and C)

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Colds are common because


A) domestic animals serve as a persistent reservoir.
B) immunity once obtained is not protective.
C) there is a lack of effective antiviral drugs.
D) of the antigenic diversity of the rhinoviruses and the lack of long-lasting immunity.

E) B) and D)
F) B) and C)

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What is the most likely reason why Reston ebolavirus does not cause human disease?


A) The human body temperature prohibits viral replication.
B) Human tissues lack the appropriate receptors for this viral strain.
C) Humans have antibodies that prevent establishment of infection with this viral strain.
D) Human interferons prevent the establishment of infection with this viral.

E) C) and D)
F) All of the above

Correct Answer

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Arthropod-borne encephalitis would show less seasonality in a tropical or subtropical climate than what is seen in a temperate climate.

A) True
B) False

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In influenza virus,antigenic shift


A) results from reassortment of genomes when two different strains of flu viruses infect the same cell.
B) results from the accumulation of mutations in HA and NA in a single strain of flu virus.
C) can result in major epidemics or pandemics.
D) results from reassortment of genomes when two different strains of flu viruses infect the same cell and can result in major epidemics or pandemics.

E) B) and D)
F) B) and C)

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West Nile virus has been detected in _________ states of the United.States.


A) 25
B) 50
C) 47
D) 10

E) B) and D)
F) None of the above

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The Epstein-Barr virus is the etiologic agent of infectious mononucleosis.

A) True
B) False

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Antigenic variation occurs almost yearly with the influenza _________ virus.


A) A
B) B
C) C
D) D

E) All of the above
F) B) and D)

Correct Answer

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Diagnosis of West Nile virus infection is through detection of


A) viral growth in cell cultures.
B) a rise in neutralizing antibody in a patient's serum.
C) PCR analysis from saliva samples.
D) culture on artificial media.

E) B) and C)
F) A) and B)

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