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In contrast to the cell cycle of adult somatic cells,the dividing cells of an early embryo lack which cell cycle stage(s) ?


A) M
B) S
C) G1 and G2
D) interphase

E) C) and D)
F) B) and C)

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Which genes are expressed in Drosophila after pattern formation along the A/P axis has been successfully established?


A) totipotent genes
B) bicoid genes
C) segment polarity genes
D) gap genes
E) homeotic genes

F) A) and D)
G) C) and E)

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E

A zygote divides into smaller cells,each called a


A) blastomere.
B) gastrula.
C) neurula.
D) cleavage cell.
E) embryonic cell.

F) C) and D)
G) D) and E)

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Which of the following statements regarding stem cells is false?


A) Totipotent stem cells can differentiate into any cell type in the body,except embryonic stem cells.
B) Pluripotent stem cells are descendants of the totipotent stem cells of the embryo.
C) A fertilized egg is a type of totipotent stem cell.
D) Pluripotent stem cells can differentiate into any cell type,except for totipotent stem cells and the cells of the placenta.

E) A) and D)
F) A) and B)

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Adult stem cells are usually


A) differentiated.
B) totipotent.
C) pluripotent.
D) multipotent.

E) A) and B)
F) C) and D)

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Scientists attempted for many years to conduct nuclear transplants but failed.However,geneticists at the Roslin Institute in Scotland had success in cloning a sheep.They were successful because they


A) picked a cell very early in development.
B) replicated the blastomeres before insertion.
C) delayed transcription in the blastomeres.
D) treated the nucleus with sheep plasma before nuclear insertion.
E) utilized a new micro pipette techniquE.

F) A) and E)
G) All of the above

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In C. elegans ced-9/ced-3 double mutants


A) 131 cells always die.
B) all 1090 cells die.
C) all 1090 cells live.
D) only 959 cells live.

E) C) and D)
F) All of the above

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Plants do not utilize the process of cell migration in their development.Instead plants utilize


A) the process of building themselves inwardly via the meristems present in the developing plant tissues.
B) the process of building themselves outwardly via the meristems present in the developing plant tissues.
C) the process of building themselves with epidermal tissues,which eventually become ground tissues,which can then begin the process of photosynthesis.
D) the process of building themselves by using their vascular tissues to form meristems,which eventually cause normal development in the plant.

E) None of the above
F) B) and D)

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B

Members of the Bcl-2 family all have Bcl-2 homology (BH) domains,which are essential for protein function.If one were to generate a transgenic worm that expresses a Bcl-2 protein containing a mutation in the BH domain in a ced-9 mutant background,


A) 131 cells would die.
B) all 1090 cells would die.
C) all 1090 cells would live.
D) 959 cells would live.

E) B) and D)
F) All of the above

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A muscle precursor cell would be considered to be


A) pluripotent.
B) determined.
C) differentiated.
D) induceD.

E) All of the above
F) A) and D)

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________ are cell adhesion proteins that some cells use for movement during their development.


A) Cadherins
B) Glycospheres
C) Receptors
D) Phospholipids

E) A) and B)
F) None of the above

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Cell transplantation experiments can be used to do all of the following except


A) to study the normal fate of cells.
B) to address the ability of cells to communicate with surrounding tissue.
C) to determine cell lineage.
D) to test the functional compatibility of cells between species.

E) A) and B)
F) A) and C)

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A complete cell lineage map exists for


A) C. elegans.
B) Drosophila.
C) mouse.
D) human.

E) C) and D)
F) B) and C)

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There are cases,particularly in fruit flies,in which a perfectly normal body part grows in an area where it should not grow.Extra pairs of wings and legs growing in the antennae location are some examples.Select the statement that best describes this phenomenon.


A) These mutations occur as a result of specialized development called determination in which the gene determining a specific factor will become totipotent.
B) These mutations occur as a result of differentiation of these tissues at the incorrect time during development,which causes a mix-up in signals and protein production in those tissues.
C) These mutations occur as a result of homeotic gene mutations.
D) These mutations occur as a result of gap gene mutations.

E) B) and D)
F) A) and B)

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In Drosophila development,which of the following choices is true?


A) Paternal genes determine the initial course of the development after fertilization.
B) Zygotic genes determine the initial course of the development after fertilization.
C) Maternal genes determine the initial course of the development after fertilization.
D) Syncytial blastoderm genes determine the initial course of the development after fertilization.

E) C) and D)
F) A) and C)

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In a 32-cell stage tunicate embryo,vegetal marginal cells that lack functional genes for both macho-1 and the FGF receptor would develop as what cell type?


A) mesenchyme
B) muscle
C) notochord
D) nerve cord

E) All of the above
F) A) and B)

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A seed germinates as a result of


A) a predetermined internal clock set in place at fertilization.
B) responses to changes in its environment.
C) having tolerated a long winter.
D) being planted at the correct time.
E) its genetics.

F) A) and C)
G) A) and E)

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B

In Drosophila,the initial cells created by cleavage contain different developmental signals from the egg called cytoplasmic _______.


A) stem cells
B) signals
C) determinants
D) junctions

E) All of the above
F) C) and D)

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Which of the following proteins is associated with activating genes that code for the first mRNA transcribed in Drosophila embryos?


A) bax protein
B) cadherin protein
C) bicoid protein
D) nanos protein
E) morphogen protein

F) A) and C)
G) C) and E)

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In Drosophila,different segmental fates of each neuroblast (cells that give rise to neurons) is determined by


A) gap genes.
B) pair-rule genes.
C) segment polarity genes.
D) homeotic genes.

E) B) and C)
F) C) and D)

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