Question 1

An important comorbidity of schizophrenia is

Accepted Answer

A)   depression.
B)   mania.
C)   gambling disorder.
D)   substance abuse disorder.
E)   borderline personality disorder.F) A) and B)
G) A) and C)

Question 2

Administration of an opiate

Accepted Answer

A)   decreases locomotor activity.
B)   raises body temperature.
C)   induces pain.
D)   causes arousal.
E)   results in reinforcement.F) B) and D)
G) B) and C)

Question 3

Research using antagonist-precipitated withdrawal indicates that the ________ plays a key role in producing opiate withdrawal symptoms.

Accepted Answer

A)   amygdala
B)   orbitofrontal cortex
C)   hypothalamus
D)   locus coeruleus
E)   reticular formationF) B) and E)
G) A) and C) D

Question 4

A common factor that promotes relapse in recovered drug addicts is

Accepted Answer

A)   the experience of stress.
B)   taking up smoking.
C)   going on a diet for weight loss.
D)   inactivation of the central nucleus of the amygdala.
E)   taking on a new career.F) B) and C)
G) D) and E)

Question 5

If a new drug is developed that is a potent CB1 antagonist, one would expect this drug to

Accepted Answer

A)   produce a "high" similar to that of marijuana.
B)   repair memory in elderly dementia patients.
C)   impair the reinforcing actions of drugs such as nicotine, cocaine and alcohol.
D)   suppress D2 receptors.
E)   produce conditioned aversion for the areas in which the drug is experienced.F) A) and D)
G) A) and B)

Question 6

The primary mode of action by which alcohol can produce apoptosis is as a(n)

Accepted Answer

A)   direct agonist at GABAA receptors.
B)   agonist at α1 adrenoceptors.
C)   direct antagonist at GABAA receptors.
D)   indirect antagonist at glycine receptors.
E)   cholinergic agonist.F) B) and E)
G) C) and D)

Question 7

Which of the following may explain why smokers obtain more pleasure from smoking in the morning than late in the afternoon?

Accepted Answer

A)   Nicotine receptors are in the open state in the morning.
B)   Nicotine receptors are in the closed state in the evening.
C)   Abstinence from nicotine has reset their nicotine receptors to the closed state.
D)   Smoking decreases the number of nicotine receptors in the brain.
E)   Smoking decreases the number of nicotine receptors outside the brain.F) A) and B)
G) A) and C)

Question 8

A possible treatment for cocaine addiction involving the immune system would be to administer

Accepted Answer

A)   antibodies to dopamine transporters.
B)   drugs that stimulate dopamine receptors.
C)   antibodies to cocaine.
D)   gamma-vinyl GABA.
E)   buprenorphine.F) A) and B)
G) A) and C) D

Question 9

Long-term drug use can result in structural abnormalities of the ________ cortex.

Accepted Answer

The answer of Long-term drug use can result in structural...

Question 10

Rats that self-injected ________ were more likely to die from an overdose than rats that self-injected ________.

Accepted Answer

The answer of Rats that self-injected ________ were more likely...

Question 11

Susceptibility to alcoholism is most likely linked to variability in

Accepted Answer

A)   family patterns of alcohol abuse.
B)   emotional dependence.
C)   reactivity to environmental stressors.
D)   lack of guilt about drinking.
E)   metabolism of alcohol.F) B) and C)
G) A) and E)

Question 12

Which of the following statements is true of cocaine?

Accepted Answer

A)   Cocaine administration decreases dopamine within the nucleus accumbens.
B)   Damage to the amygdale impairs cocaine reinforcement.
C)   Cocaine abuse can produce obsessive-compulsive disorder.
D)   Drugs that block GABA receptors within the nucleus accumbens impair cocaine reinforcement.
E)   Rats will self-administer cocaine into their vascular system.F) A) and C)
G) D) and E)

Question 13

The common aspect of all natural reinforcers relates to

Accepted Answer

A)   the release of dopamine within the nucleus accumbens.
B)   the release of norepinephrine within the locus coeruleus.
C)   the release of dopamine within the lateral hypothalamus.
D)   inactivation of the frontal cortex.
E)   activation of the medulla.F) D) and E)
G) C) and D)

Question 14

The meaning of the Latin word addicere is

Accepted Answer

A)   to alleviate.
B)   to relieve.
C)   to sentence.
D)   to require.
E)   to suffer.F) None of the above
G) C) and D)

Question 15

The use of ________ by pregnant women leads to reduced birth weight.

Accepted Answer

A)   ethyl alcohol
B)   marijuana
C)   morphine in pill form
D)   cocaine in powder form
E)   nicotine in tobaccoF) A) and C)
G) A) and D)

Question 16

A person who is compelled to continue drug taking, despite adverse consequences, is said to suffer from

Accepted Answer

A)   addiction.
B)   psychic dependence.
C)   tolerance.
D)   physical dependence.
E)   euphoria.F) All of the above
G) A) and B)

Question 17

Match up the correct pairing of opiate receptor and opiate effect:

Accepted Answer

A)   mu; sedating
B)   delta; aversive
C)   kappa; aversive
D)   mu; aversive
E)   mu; reinforcingF) B) and E)
G) C) and D)

Question 18

Match up the correct pairing of a drug with its site of action:

Accepted Answer

A)   cocaine; nicotinic ACh receptor agonist
B)   ethanol; release of norepinephrine
C)   amphetamine; release of dopamine
D)   ketamine; blocks reuptake of dopamine
E)   cannabis; nicotinic ACh receptor agonistF) C) and D)
G) A) and E)

Question 19

Match up the correct pairing of a drug with its site of action:

Accepted Answer

A)   cocaine; blocks reuptake of dopamine
B)   ethanol;release of norepinephrine
C)   amphetamine; release of acetylcholine
D)   ketamine; blocks reuptake of dopamine
E)   cannabis; nicotinic ACh receptor agonistF) C) and E)
G) A) and E) A

Question 20

Which of the following is an adverse consequence of the use of "designer drugs"?

Accepted Answer

A)   stroke
B)   toxic consequences of drug adulteration
C)   diabetes
D)   heart disease
E)   lung cancerF) A) and D)
G) B) and E)

Exam 18: Drug Abuse

An important comorbidity of schizophrenia is

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Administration of an opiate

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Research using antagonist-precipitated withdrawal indicates that the ________ plays a key role in producing opiate withdrawal symptoms.

Correct AnswerverifiedD

A common factor that promotes relapse in recovered drug addicts is

Correct AnswerverifiedShow Answer

If a new drug is developed that is a potent CB1 antagonist, one would expect this drug to

Correct AnswerverifiedShow Answer

The primary mode of action by which alcohol can produce apoptosis is as a(n)

Correct AnswerverifiedShow Answer

Which of the following may explain why smokers obtain more pleasure from smoking in the morning than late in the afternoon?

Correct AnswerverifiedShow Answer

A possible treatment for cocaine addiction involving the immune system would be to administer

Correct AnswerverifiedD

Long-term drug use can result in structural abnormalities of the ________ cortex.

Correct AnswerverifiedShow Answer

Rats that self-injected ________ were more likely to die from an overdose than rats that self-injected ________.

Correct AnswerverifiedShow Answer

Susceptibility to alcoholism is most likely linked to variability in

Correct AnswerverifiedShow Answer

Which of the following statements is true of cocaine?

Correct AnswerverifiedShow Answer

The common aspect of all natural reinforcers relates to

Correct AnswerverifiedShow Answer

The meaning of the Latin word addicere is

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The use of ________ by pregnant women leads to reduced birth weight.

Correct AnswerverifiedShow Answer

A person who is compelled to continue drug taking, despite adverse consequences, is said to suffer from

Correct AnswerverifiedShow Answer

Match up the correct pairing of opiate receptor and opiate effect:

Correct AnswerverifiedShow Answer

Match up the correct pairing of a drug with its site of action:

Correct AnswerverifiedShow Answer

Match up the correct pairing of a drug with its site of action:

Correct AnswerverifiedA

Which of the following is an adverse consequence of the use of "designer drugs"?

Correct AnswerverifiedShow Answer

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D

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D

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Rats that self-injected were more likely to die from an overdose than rats that self-injected .

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A

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